Sunday, June 20, 2010

Young Barley Grass Scientific/Clinical Studies, Papers, more...

Below are some compilation of scientific and clinical studies, and papers of Young Barley Leaves, this content will be updated more often for the latest and new developments...


Badamchian, M.; Naylor, P.H.; Spangelo, B.; Strickler, M.P.; Stone, M.J.; Hagiwara, Y.; Hagiwara, H.; and Goldstein, A.L. 1991. "Immune-endocrine Activities of Green Barley Leaf Extract (BLE): Regulation of Prolactin and Interleukin-2 Release in Vitro." FASEB Journal, Vol. 5, No. 4.


Badamchian, M.; Spangelo, B.; Bao, Y.; Hagiwara, Y.; Hagiwara, H.; Ueyama, H.; and Goldstein, A. 1994. "Isolation of a Vitamin E Analog From a Green Barley Leaf Extract That Stimulates Release of Prolactin and Growth Hormone From Rat Anterior Pituitary Cells in Vitro." The Journal of Nutritional Biochemistry, Vol. 5, March, 1994.

Hotta, Y. 1984. "Stimulation of DNA Repair-synthesis by P4-D I, One of the Novel Components of Barley Extracts." Lecture given in Honolulu, Hawaii.

Kitta, K.; Hagiwara, Y.; and Shibamoto, T. 1992. "Antioxidative Activity of an Isoflavonoid, 2"-O-Glycosylisovitexin Isolated From Green Barley Leaves." Journal of Agricultural and Food Chemistry, Vol. 40, No. 10.

S. Nakajima, Y. Hagiwara, H. Hagiwara, and T. Shibamoto. Effect of the Antioxidant 2"-O-Glycosylisovitexin from young green barley leaves on acetaldehyde formation in beer stored at 50 °C for 90 days. 1998, Journal of Agricultural and Food Chemistry, Vol. 46 (4), 1529-1531.

Durham, J., Ogata, J., Nakajima, S., Hagiwara, Y., and Shibamoto, T. Degradation of organophosphorus pesticides in aqueous extracts of young green barley leaves (Hordeum vulgare L). 1999, J. of the Science of Food and Agriculture.

Kubota, K., and Sunagane, N. 1984. "Studies on the Effects of Green Barley Juice on the Endurance and Motor Activity in Mice." Paper presented at The 104th Annual Congress of The Pharmaceutical Society of Japan in Sendai City, Japan.

Kubota, K.; and Matsuoka, Y. 1984. "Effect of Chronic Administration of Green Barley Juice on Growth Rate, Serum Cholesterol Level, and Internal Organs of Mice." Paper presented at The 104th Annual Congress of The Pharmaceutical Society of Japan, Sendai City, Japan.

Kubota, K.; Matsuoka, Y.; and Seki, H. 1983. "Isolation of Potent Anti-Inflammatory Protein From Barley Leaves." The Japanese journal of Inflammation, Vol. 3, No. 4.

Moussazadeh, M.; Badamchian, M.; Hagiwara, Y.; Hagiwara, H.; and Goldstein, A. "Effect of Green Barley Leaf Extract (BLE) on Human Platelets in Vitro." Presentation at the 1992 FASEB (Federation of American Societies for Experimental Biology), Anaheim, CA.

Muto, Tatsuo. 1977. "Therapeutic Experiment of Bakuryokuso(Young Green Barley Juice) for the Treatment of Skin Diseases in Man." New Drugs and Clinical Application, Vol. 26, No. 5.

Nishiyama, Tadashi. "Study of Young Barley Leaf Extract: The Antioxidant Compound and Its Effect, July 1991 -June 1993." Unpublished study.

Nishiyama, T.; Hagiwara, Y.; Hagiwara, H.; and Shibamoto, T. 1993. "Inhibition of Malonaldehyde Formation from Lipids by an Isoflavonoid Isolated From Young Green Barley Leaves." Journal of the American Oil Chemists' Society Vol. 70, No. 8.

Ohtake, H.; Nonaka, S.; Sawada, Y.; Hagiwara, Y.; Hagiwara, H.; and Kubota, K. 1985. "Studies on the Constituents of Green Juice From Young Barley Leaves (Effect on Dietarily Induced Hypercholesterolernia in Rats)." Journal of The Pharmaceutical Society of Japan, Vol. 105, No. 11.

Ohtake, H.; Yuasa, H.; Komura, C.; Miyauchi, T.; Hagiwara, Y.; and Kubota, K. 1985. "Studies on the Constituents of Green Juice From Young Barley Leaves (Anti-Ulcer Activity of Fractions From Barley Juice)." Journal of The Pharmaceutical Society of Japan, Vol. 105, No. 11.

Osawa, T.; Katsuzaki, H.; Hagiwara, Y.; Hagiwara, H.; and Shibamoto, T. 1992. "A Novel Antioxidant Isolated From Young Green Barley Leaves." Journal of Agricultural and Food Chemistry, Vol. 40, No. 7. : 1135-1138

Shibamoto, T.; Hagiwara, Y.; Hagiwara, H.; and Osawa, 11994. "A Flavonoid With Strong Antioxidative Activity Isolated From Young Green Barley Leaves." Food Phytochemicals for Cancer Prevention IL Edited by Chi-Tang Ho, Toshihiko Osawa, Mou-Tuan Huany, and Robert T. Rosen. Washington, D.C: ACS Symposium Series. American Chemical Association.

Wagner, Eugene S. and Raman Mocharla. 1991. "Immune System Components Altered by a Food Supplement." Paper presented at the 1991 Annual Meeting of the American Association for the Advancement of Science February 16, 1991; Washington D.C. Those given the barley leaf extract exhibited a statistically significant increase in the percentage of their leukocytes that were neutrophils and in circulating complement levels as well as statistically significant decreases in percent lymphocytes and monocytes.

Yokono, 0. "Therapeutic Effect of Water-Soluble Form of Chlorophyll-A and the Related Substance the Young Green Barley juice in the Treatment of Patients with Chronic Pancreatitis." Published privately.

Gromley, James J. "Green leaves of barley ease arthritis for some" Better Nutrition for Today's Living , Sep95, Vol. 57 Issue 9, p42, 1p, 1c Reports on the beneficial effects of barley juice for arthritis sufferers. Harmful effects of aspirin or non-steroidal anti-inflammatory drugs traditionally prescribed by doctors; Ancient origin of barley; Nutritional value of barley juice; Other medical conditions that can be treated with barley juice; Barley-producing states.

Murray, Frank " Unless you balance acidity, your muscles may become tense." Better Nutrition, Mar96, Vol. 58 Issue 3, p26, 1p, 1c Discusses the flexibility of muscles in terms of balancing acidity. How acidity is measured; Connection to exercise; Inhibitors of exercise; Explanations from Michael Colgan, Ph.D.; Benefits of barley juice.

"Green barley grass may help arthritics." Better Nutrition for Today's Living, Jul95, Vol. 57 Issue 7, p32, 1p, 1c Reports that physicians have recommended green barley juice supplements as part of arthritis therapy. Response of patients to the barley treatments; Elimination of nonsteroidal anti-inflammatory drugs.

Yu YM; Wu CH; Tseng YH; Tsai CE; Chang WC "Antioxidative and hypolipidemic effects of barley leaf essence in a rabbit model of atherosclerosis." Japanese journal of pharmacology 2002 Jun; Vol. 89 (2), pp. 142-8. The results suggest that the antioxidant and hypolipidemic effects of barley leaf essence could be useful in the prevention of cardiovascular disease in which atherosclerosis is important.

Yu YM; Chang WC; Chang CT; Hsieh CL; Tsai CE "Effects of young barley leaf extract and antioxidative vitamins on LDL oxidation and free radical scavenging activities in type 2 diabetes. " Diabetes & metabolism [Diabetes Metab] 2002 Apr; 28 (2), pp. 107-14. Results indicate that supplementation with BL may help to scavenge oxygen free radicals, save the LDL-vitamin E content, and inhibit LDL oxidation. Furthermore, the addition of vitamins C and E to BL can inhibit the Sd-LDL oxidation more effectively, which may protect against vascular diseases in type 2 diabetic patients.

Janis J Durham, Joji Ogata, Sadatoshi Nakajima, Yoshihide Hagiwara, Takayuki Shibamoto; "Degradation of organophosphorus pesticides (malathion, chlorpyrifos, guthion, diazinon, methidathion and parathion) in aqueous extracts of young green barley leaves (Hordeum vulgare L)"; Department of Environmental Toxicology, University of California, Davis, CA 95616; Journal of the Science of Food and Agriculture Volume 79, Issue 10, 1999, pages 1311-1314. An abstract is available at http://www3.interscience.wiley.com/cgi-bin/abstract/62003336/START

Dr. Allan L. Goldstein, Ph.D, George Washington Univ. Medical Center "Barley grass leaf extract dramatically inhibits the growth of human prostatic cancer cells grown in tissue culture. ...It may provide a new nutritional approach to the treatment of prostate cancer."


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BARLEY JUICE SCIENTIFIC FINDINGS




Good reports abound on the benefits of barley juice. Scientists have only scratched the surface in understanding why barley juice has helped so many. What is in barley juice? Scientists have found

 a substance to actually stimulate repair of the DNA molecule

 a protein with strong anti-inflammatory qualities

 substances that reduced hypercholesterolemia

 substances that resulted in an anti-ulcer effect

 components in barley leaf extract which de-activate mutagenic and carcinogenic substances

 an enzyme called SOD which is an extremely powerful 'anti-aging' antioxidant, an anti-inflammatory enzyme and cancer preventive enzyme

 another powerful antioxidant, 2'-0-GlV, more effective than vitamin E

 components in barley leaf extract which were very effective in lowering the blood sugar levels in high blood sugar mice

 substances which help to inhibit platelet activating factor

 substances which protect the blood vessels from damage

 it improves or modulates Prolactin and growth hormone

 barley juice degrades a variety of pesticides - Detoxification implications.

 5 enzymes were found that help the decomposition of fats in the body proceed smoothly which helps to promote correct body weight.

An enzyme called P4D1, isolated in a laboratory in California in the 1980's in Barley juice. P4D1 was found to do two things in the human body. It is the first known substance to actually stimulate repair of the DNA molecule. It is possible that disease cells can be repaired with P4D1 so that when they reproduce they will actually produce good cells. P4D1 has also been shown in laboratory tests to eat the protein sheath off a cancer cell so that the white blood cells can attack and destroy them.



1983 - Successfully isolated a protein in barley leaf extract with strong anti-inflammatory qualities.



1985 - discovery of substances in barley leaf extract that reduced hypercholesterolemia and substances that resulted in an anti-ulcer effect



1985 - successfully identified the presence of some components in barley leaf extract which de-activate mutagenic and carcinogenic substances



SOD or superoxide dismutase has been isolated, which is an extremely powerful 'anti-aging' antioxidant. The aging process has been directly linked to decreasing amounts of SOD in our system. Increased amounts of SOD cause our body to repair itself quicker. Additionally SOD acts as an anti inflammatory enzyme and cancer preventive enzyme. Pure Young Barley is rich in SOD - one of the richest sources available today. SOD converts a harmful substance called superoxide, into water and oxygen which is completely harmless.



Peroxidase was isolated which actually breaks down and neutralizes Try-P1 and P2 a carcinogen in grilled meat and fish and 3-4benzypyrene, another carcinogen in tobacco.



Observed were water soluble components in barley leaf extract which were very effective in lowering the blood sugar levels in high blood sugar mice, which would greatly benefit diabetics and hypoglycemics.



George Washington University, One study reported on the important substances found in barley leaf extract which help to inhibit platelet activating factor and to protect the blood vessels from damage. These substances are even effective throughout the micro-circulatory system, protecting the smallest vessels from damage.



In 1994, at the same University, a Vitamin E succinate was identified. This was shown to improve or modulate Prolactin and growth hormone. Prolactin is vital to breast feeding moms, so breast feeding Moms should benefit from taking barley juice. Growth hormone will benefit children and those that are overweight. This has implications in helping to improve immunological functions and slowing down the process of aging.



UC Davis, looked at the potential for barley leaf extract to degrade a common pesticide, malathion, in vitro. Six different experiments where performed to measure the ability of barley leaf extract to "detoxify" this pesticide. Every one of the studies revealed very positive results. This study leads us to believe that barley leaf extract may provide a cleansing, or detoxifying benefit when pesticide accumulation has occurred in the body. The article can be found in Volume 79, Issue 10, 1999, pages 1311-1314 of Journal of the Science of Food and Agriculture. An abstract is available at http://www3.interscience.wiley.com/cgi-bin/abstract/62003336/START



At the University of Davis - successfully identified a new substance in barley leaf extract which contains very impressive antioxidant properties. This substance is called 2'-O-Glycosylisovitexin. They have been able to demonstrate that it is more effective as an antioxidant than beta carotene or vitamin E.



UC Davis - successfully identified several of the characteristics of 2'-0-Glycosylisovitexin. They have now confirmed that it is water soluble substance, it is stable, both in high temperatures and within a wide range of pH. It is also very effective as an antioxidant in lipid peroxidation caused by ultra violet irradiation. This confirms our earlier hypotheses that 2'-0-GIV may play a preventative role in aging, mutagenesis, carcinogenesis and radiation damage.



It is also interesting to note that the majority of green products available for purchase today do not contain active 2'-0-GIV.



There have been a lot of anecdotal reports where children and overweight people benefited from barley juice. Fatty Acid Oxidase, cytochrome oxidase, peroxidase, Catalase and Transhydrogenase are enzymes found in barley juice that help the decomposition of fats in the body proceed smoothly which also helps to promote correct body weight, without these enzymes, weight gain results.

2 comments:

Unknown said...

This is great! People should know these findings..

nogurus said...

Wonderful job Eric! Thank you

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